TNFa, Recombinant, Mouse, aa80-235 (Tumor necrosis factor)

Product Overview

• Article Name: TNFa, Recombinant, Mouse, aa80-235 (Tumor necrosis factor)
• Biozol Catalog Number: USB-350335
• Supplier Catalog Number: 350335
• Alternative Catalog Number: USB-350335-100, USB-350335-500
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

TNFa, also known as tumor necrosis factor, binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia. Source: Recombinant protein corresponding to aa80-235 of mouse TNFa expressed in E. coli. Accession: NP_038721 Molecular Weight: ~17.4kD Amino Acid Sequence: MLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIAL Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 17.4
• NCBI: 038721
• UniProt: P01375
• Purity: 95% (SDS-PAGE)
• Form: Supplied as a liquid in PBS, pH 7.4. No preservative added.