TXNL1, Recombinant, Human, aa1-289, His-Tag (Thioredoxin-like protein 1)

Catalog Number: USB-350360
Article Name: TXNL1, Recombinant, Human, aa1-289, His-Tag (Thioredoxin-like protein 1)
Biozol Catalog Number: USB-350360
Supplier Catalog Number: 350360
Alternative Catalog Number: USB-350360-100, USB-350360-500
Manufacturer: US Biological
Category: Molekularbiologie
TXNL1, also known as TRP32, TXL or TXL-1, is a cytoplasmic protein that participates in endocytotic signaling pathways and acts as a redox sensor. Expressed throughout the body, TXNL1 functions to couple oxidative stress to endocytosis, thereby regulating the GDI. Additionally, overexpression of TXNL1 inhibits cell proliferation by predisposing the cell to G0/G1 arrest, suggesting that TXNL1 also functions as a transcriptional repressor. Source: Recombinant protein corresponding to human TXNL1, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~34.4kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MVGVKPVGSD PDFQPELSGA GSRLAVVKFT MRGCGPCLRI APAFSSMSNK YPQAVFLEVD VHQCQGTAAT NNISATPTFL FFRNKVRIDQ YQGADAVGLE EKIKQHLEND PGSNEDTDIP KGYMDLMPFI NKAGCECLNE SDEHGFDNCL RKDTTFLESD CDEQLLITVA FNQPVKLYSM KFQGPDNGQG PKYVKIFINL PRSMDFEEAE RSEPTQALEL TEDDIKEDGI VPLRYVKFQN VNSVTIFVQS NQGEEETTRI SYFTFIGTPV QATNMNDFKR VVGKKGESH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 34.4
NCBI: 004777
Purity: 95% (SDS-PAGE)
Form: Supplied as a liquid in 20mM Tris-HCI, pH 8.0, 0.2M sodium chloride, 5mM DTT, 20% glycerol.