UTP23, Recombinant, Human, aa1-249, His-Tag (RNA-processing protein uTP23 homolog)
Biozol Catalog Number:
USB-350383
Supplier Catalog Number:
350383
Alternative Catalog Number:
USB-350383-100, USB-350383-500
Manufacturer:
US Biological
Category:
Molekularbiologie
RNA-processing protein uTP23 homolog, also known as uTP23, is a small subunit (SSu) processome component. The SSu processome is a complex involved in ribosome biogenesis and is required for pre-18S rRNA maturation. uTP23 is required for the first three cleavage steps in 18S rRNA maturation. In addition, single-point mutations in the conserved putative active site of utp24 but not utp23 abrogate its function in ribosome biogenesis. Source: Recombinant protein corresponding to aa1-249 of human UTP23, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~30.8kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMKITRQK HAKKHLGFFR NNFGVREPYQ ILLDGTFCQA ALRGRIQLRE QLPRYLMGET QLCTTRCVLK ELETLGKDLY GAKLIAQKCQ VRNCPHFKNA VSGSECLLSM VEEGNPHHYF VATQDQNLSV KVKKKPGVPL MFIIQNTMVL DKPSPKTIAF VKAVESGQLV SVHEKESIKH LKEEQGLVKN TEQSRRKKRK KISGPNPLSC LKKKKKAPDT QSSASEKKRK RKRIRNRSNP KVLSEKQNAE GE Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
