ACTA2, Recombinant, Human, aa3-377, His-Tag (Actin, aortic smooth muscle, AAT6, ACTSA, MYMY5)

Product Overview

• Article Name: ACTA2, Recombinant, Human, aa3-377, His-Tag (Actin, aortic smooth muscle, AAT6, ACTSA, MYMY5)
• Biozol Catalog Number: USB-351054
• Supplier Catalog Number: 351054
• Alternative Catalog Number: USB-351054-50,USB-351054-250
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

ACTA2 belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. Recombinant protein corresponding to aa3-377 from human ACTA2, fused to His-tag at N-terminal expressed in E. coli Swiss/UniProt Accession: P62736. Molecular Weight: ~44.4kD (400aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHM EEEDS TALVCDNGSG LCKAGFAGDD APRAVFPSIV GRPRHQGVMV GMGQKDSYVG DEAQSKRGIL TLKYPIEHGI ITNWDDMEKI WHHSFYNELR VAPEEHPTLL TEAPLNPKAN REKMTQIMFE TFNVPAMYVA IQAVLSLYAS GRTTGIVLDS GDGVTHNVPI YEGYALPHAI MRLDLAGRDL TDYLMKILTE RGYSFVTTAE REIVRDIKEK LCYVALDFEN EMATAASSSS LEKSYELPDG QVITIGNERF RCPETLFQPS FIGMESAGIH ETTYNSIMKC DIDIRKDLYA NNVLSGGTTM YPGIADRMQK EITALAPSTM KIKIIAPPER KYSVWIGGSI LASLSTFQQM WISKQEYDEA GPSIVHRKCF Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 44.4
• NCBI: 001604
• UniProt: P62736
• Purity: 85% (SDS-PAGE)
• Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.15M sodium chloride, 10% glycerol