CD5L, also known as CD5 antigen-like, plays a role in the regulation of the immune system. CD5L which is a secreted glycoprotein and expressed by macrophages presenting lymphoid tissues such as bone marrow, lymph node and thymus is up-regulated in macrophage at inflammatory sites. It sustains inflammatory reactions by both increasing the phagocytic capacity of macrophage and impeding the apoptosis of local macrophages, NK cells and T cells. Recombinant protein corresponding to aa22-352 from mouse CD5L, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~37.6kD (339aa) Amino Acid Sequence: ESPTKVQLVG GAHRCEGRVE VEHNGQWGTV CDDGWDRRDV AVVCRELNCG AVIQTPRGAS YQPPASEQRV LIQGVDCNGT EDTLAQCELN YDVFDCSHEE DAGAQCENPD SDLLFIPEDV RLVDGPGHCQ GRVEVLHQSQ WSTVCKAGWN LQVSKVVCRQ LGCGRALLTY GSCNKSTQGK GPIWMGKMSC SGQEANLRSC LLSRLENNCT HGEDTWMECE DPFELKLVGG DTPCSGRLEV LHKGSWGSVC DDNWGEKEDQ VVCKQLGCGK SLHPSPKTRK IYGPGAGRIW LDDVNCSGKE QSLEFCRHRL WGYHDCTHKE DVEVICTDFD VLEHHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
