EYA2, Recombinant, Human, aa244-514, His-Tag (Eyes absent homolog 2, EAB1)

Product Overview

• Article Name: EYA2, Recombinant, Human, aa244-514, His-Tag (Eyes absent homolog 2, EAB1)
• Biozol Catalog Number: USB-351217
• Supplier Catalog Number: 351217
• Alternative Catalog Number: USB-351217-50,USB-351217-250
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

EYA2, also known as eyes absent homolog 2, is a member of tyrosine phosphatase family that specifically dephosphorylates Tyr-142 of histone H2AX (H2AXY142ph). This protein promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Recombinant protein corresponding to aa244-514 from human EYA2, fused to His-Tag at N-terminal, expressed in E. coli. Accession: AAH08803 Molecular Weight: ~33.2kD (295aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMERVFVW DLDETIIIFH SLLTGTFASR YGKDTTTSVR IGLMMEEMIF NLADTHLFFN DLEDCDQIHV DDVSSDDNGQ DLSTYNFSAD GFHSSAPAAN LCLGSGVHGG VDWMRKLAFR YRRVKEMYNT YKNNVGGLIG TPKRETWLQL RAELEALTDL WLTHSLKALN LINSRPNCVN VLVTTTQLIP ALAKVLLYGL GSVFPIENIY SATKTGKESC FERIMQRFGR KAVYVVIGDG VEEEQGAKKH NMPFWRISCH ADLEALRHAL ELEYL Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Properties

• Molecular Weight: 33.2
• NCBI: 08803
• UniProt: O00167
• Purity: 80% (SDS-PAGE).
• Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.15M sodium chloride, 1mM DTT, 40% glycerol.