KLRC2, Recombinant, Human, aa94-231, His-Tag (NKG2-C type II integral membrane protein, CD159c, NKG2-C, NKG2C)
Biozol Catalog Number:
USB-351330
Supplier Catalog Number:
351330
Alternative Catalog Number:
USB-351330-50,USB-351330-250
Manufacturer:
US Biological
Category:
Molekularbiologie
NKG2-C type II integral membrane protein, also known as KLRC2, plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. Recombinant protein corresponding to aa94-231 from human KLRC2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~18.4kD (162aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMIPFLEQ NNFSPNTRTQ KARHCGHCPE EWITYSNSCY YIGKERRTWE ESLLACTSKN SSLLSIDNEE EMKFLASILP SSWIGVFRNS SHHPWVTING LAFKHKIKDS DNAELNCAVL QVNRLKSAQC GSSMIYHCKH KL Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
