PECAM1, Recombinant, Human, aa28-601, His-Tag (Platelet endothelial cell adhesion molecule, CD31, CD31/EndoCAM, endoCAM, GPIIA, PECA1, PECAM-1)
Catalog Number:
USB-351421
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| Article Name: | PECAM1, Recombinant, Human, aa28-601, His-Tag (Platelet endothelial cell adhesion molecule, CD31, CD31/EndoCAM, endoCAM, GPIIA, PECA1, PECAM-1) |
| Biozol Catalog Number: | USB-351421 |
| Supplier Catalog Number: | 351421 |
| Alternative Catalog Number: | USB-351421-50,USB-351421-100,USB-351421-250 |
| Manufacturer: | US Biological |
| Category: | Molekularbiologie |
| PECAM1, also known as platelet endothelial cell adhesion molecule, induces susceptibility to atherosclerosis. It prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes. The encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cells active repulsion from the phagocyte. Recombinant protein corresponding to aa28-601 from human PECAM1, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~65.5kD (582aa) Amino Acid Sequence: QENSFTINSV DMKSLPDWTV QNGKNLTLQC FADVSTTSHV KPQHQMLFYK DDVLFYNISS MKSTESYFIP EVRIYDSGTY KCTVIVNNKE KTTAEYQVLV EGVPSPRVTL DKKEAIQGGI VRVNCSVPEE KAPIHFTIEK LELNEKMVKL KREKNSRDQN FVILEFPVEE QDRVLSFRCQ ARIISGIHMQ TSESTKSELV TVTESFSTPK FHISPTGMIM EGAQLHIKCT IQVTHLAQEF PEIIIQKDKA IVAHNRHGNK AVYSVMAMVE HSGNYTCKVE SSRISKVSSI VVNITELFSK PELESSFTHL DQGERLNLSC SIPGAPPANF TIQKEDTIVS QTQDFTKIAS KSDSGTYICT AGIDKVVKKS NTVQIVVCEM LSQPRISYDA QFEVIKGQTI EVRCESISGT LPISYQLLKT SKVLENSTKN SNDPAVFKDN PTEDVEYQCV ADNCHSHAKM LSEVLRVKVI APVDEVQISI LSSKVVESGE DIVLQCAVNE GSGPITYKFY REKEGKPFYQ MTSNATQAFW TKQKASKEQE GEYYCTAFNR ANHASSVPRS KILTVRVILA PWKKVEHHHH HH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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