S100A10 also known as S100 calcium binding protein A10 is a group of small Ca2+ binding proteins with molecular weight of 10-12kD. Intracellular S100 proteins usually function as modulators of their target proteins, and exert various roles such as regulation of protein phosphorylation, enzyme activity, Ca2+ homeostasis, cytoskeleton components, and transcription factors. Recent research suggests a role for S100A10 as a prognostic marker and potential therapeutic target in colorectal cancer. Source: Recombinant protein corresponding to aa1-97 from mouse S100A10, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~13.6kD (120aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMPSQMEH AMETMMLTFH RFAGDKDHLT KEDLRVLMER EFPGFLENQK DPLAVDKIMK DLDQCRDGKV GFQSFLSLVA GLTIACNDYF VVNMKQKGKK Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
