Recombinant, Human, aa23-226, His-Tag (SLAM family member 7, CD2 subset 1, CD2-like Receptor-activating cytotoxic cells, CRACC, CS1, CD319)
Biozol Catalog Number:
USB-351477
Supplier Catalog Number:
351477
Alternative Catalog Number:
USB-351477-50,USB-351477-250
Manufacturer:
US Biological
Category:
Molekularbiologie
SLAMF7, also known as SLAM family member 7, is a single-pass type 1 membrane protein and a member of the CS2 family of cell surface receptors. Isoform 1 of this protein mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. SLAMF7 can exert activating of inhibitory influences on cells of the immune system depending on cellular context and the availability of effector proteins. Source: Recombinant protein corresponding to aa23-226 from human SLAMF7, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~23.4kD (212aa) Amino Acid Sequence: SGPVKELVGS VGGAVTFPLK SKVKQVDSIV WTFNTTPLVT IQPEGGTIIV TQNRNRERVD FPDGGYSLKL SKLKKNDSGI YYVGIYSSSL QQPSTQEYVL HVYEHLSKPK VTMGLQSNKN GTCVTNLTCC MEHGEEDVIY TWKALGQAAN ESHNGSILPI SWRWGESDMT FICVARNPVS RNFSSPILAR KLCEGAADDP DSSMLEHHHH HH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
