SCN3B, Denatured, Recombinant, Human, aa23-159, His-Tag (Sodium channel Subunit beta-3 precursor, Sodium channel, voltage-gated, type III, beta Subunit, HSA243396, SCNB3)
Biozol Catalog Number:
USB-351490
Supplier Catalog Number:
351490
Alternative Catalog Number:
USB-351490-50,USB-351490-250
Manufacturer:
US Biological
Category:
Molekularbiologie
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN3B is one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified. Recombinant protein corresponding to aa23-159 from human SCN3B, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~18.1kD (160aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSFPVCVEV PSETEAVQGN PMKLRCISCM KREEVEATTV VEWFYRPEGG KDFLIYEYRN GHQEVESPFQ GRLQWNGSKD LQDVSITVLN VTLNDSGLYT CNVSREFEFE AHRPFVKTTR LIPLRVTEEA GEDFTSVVSE Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
