Syntaxin-2, also known as STX2, belongs to thesyntaxin/epimorphin family of proteins. Syntaxin family is cellular receptors for transport vesicles which participate in exocytosis in neutrophils. STX2 is a t-SNARE that localizes to the apical plasma membrane and intracellular vesicular structures. Also, STX2, along with SNAP- 23, is required for regulated surfactant secretion. Recombinant protein corresponding to aa1-264 from human STX2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~33.6kD (289aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMMRDRL PDLTACRKND DGDTVVVVEK DHFMDDFFHQ VEEIRNSIDK ITQYVEEVKK NHSIILSAPN PEGKIKEELE DLNKEIKKTA NKIRAKLKAI EQSFDQDESG NRTSVDLRIR RTQHSVLSRK FVEAMAEYNE AQTLFRERSK GRIQRQLEIT GRTTTDDELE EMLESGKPSI FTSDIISDSQ ITRQALNEIE SRHKDIMKLE TSIRELHEMF MDMAMFVETQ GEMINNIERN VMNATDYVEH AKEETKKAIK YQSKARRKK Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
