TBPL1, Recombinant, Human aa1-186, His-Tag (TATA box-binding protein-like protein 1, STUD, TLF, TLP, TRF2)
Biozol Catalog Number:
USB-351513
Supplier Catalog Number:
351513
Alternative Catalog Number:
USB-351513-50,USB-351513-250
Manufacturer:
US Biological
Category:
Molekularbiologie
BPL1, also known as STUD, TLF, TLP and TRF2, belongs to the TBP family. The TATA box-binding protein (TBP) is an essential component of the basal transcriptional machinery. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes. Source: Recombinant protein corresponding to aa1-186 from human TBPL1 fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~23.3kD(209aa), AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDADSDV ALDILITNVV CVFRTRCHLN LRKIALEGAN VIYKRDVGKV LMKLRKPRIT ATIWSSGKII CTGATSEEEA KFGARRLARS LQKLGFQVIF TDFKVVNVLA VCNMPFEIRL PEFTKNNRPH ASYEPELHPA VCYRIKSLRA TLQIFSTGSI TVTGPNVKAV ATAVEQIYPF VFESRKEIL Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
