TMOD3, Recombinant, Human, aa1-352, His-Tag (Tropomodulin-3, Tropomodulin 3, U-Tmod, UTMOD, Ubiquitous tropomodulin)

Catalog Number: USB-351531
Article Name: TMOD3, Recombinant, Human, aa1-352, His-Tag (Tropomodulin-3, Tropomodulin 3, U-Tmod, UTMOD, Ubiquitous tropomodulin)
Biozol Catalog Number: USB-351531
Supplier Catalog Number: 351531
Alternative Catalog Number: USB-351531-50,USB-351531-250
Manufacturer: US Biological
Category: Molekularbiologie
TMOD3 belongs to the tropomodulin family. Regulation of the actin cytoskeleton by filament capping proteins is critical to myriad dynamic cellular functions. The ability of these proteins to bind both filaments as well as monomers is often central to their cellular functions. The ubiquitous pointed end capping protein TMOD3 acts as a negative regulator of cell migration, yet mechanisms behind its cellular functions are not understood. Recombinant protein corresponding to aa1-352 from human TMOD3, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~42kD (376aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMALPFR KDLEKYKDLD EDELLGNLSE TELKQLETVL DDLDPENALL PAGFRQKNQT SKSTTGPFDR EHLLSYLEKE ALEHKDREDY VPYTGEKKGK IFIPKQKPVQ TFTEEKVSLD PELEEALTSA SDTELCDLAA ILGMHNLITN TKFCNIMGSS NGVDQEHFSN VVKGEKILPV FDEPPNPTNV EESLKRTKEN DAHLVEVNLN NIKNIPIPTL KDFAKALETN THVKCFSLAA TRSNDPVATA FAEMLKVNKT LKSLNVESNF ITGVGILALI DALRDNETLA ELKIDNQRQQ LGTAVELEMA KMLEENTNIL KFGYQFTQQG PRTRAANAIT KNNDLVRKRR VEGDHQ Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 42
NCBI: 055362
UniProt: Q9NYL9
Purity: 80% (SDS-PAGE)
Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.15M sodium chloride, 10% glycerol.