IBMX (3-Isobutyl-1-methylxanthine), CAS [[28822-58-4]]
Biozol Catalog Number:
USB-351831
Supplier Catalog Number:
351831
Alternative Catalog Number:
USB-351831-50
Manufacturer:
US Biological
Category:
Biochemikalien
3-isobutyl-1-methylxanthine (IBMX) is a nonselective inhibitor of cAMP and cGMP phosphodiesterases (PDEs). Research studies show that IBMX inhibits many members of the PDE family, with the exceptions of PDE8A, PDE8B, and PDE9 (1-4). Treatment of cells with IBMX promotes accumulation of cAMP and cGMP, which leads to activation of cyclic- nucleotide- regulated protein kinases (5,6). Additional research indicates that IBMX can promote neuronal progenitor cell maturation in vitro (7). Formula: C10H14N4O2 Solubility: Soluble in DMSO up to ~222mg/ml (1M) with warming. Soluble in DMF or ethanol at 5mg/ml. Molecular Weight: 222.30g/mol Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
222.3
Purity:
Highly Purified (~98%)
Form:
Supplied as a lyophilized powder. For a 250mM stock, reconstitute the 50mg in 899.7ul DMSO.
CAS Number:
[28822-58-4]
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