FXR (Farnesoid X Receptor, NR1H4, BAR, FXR, HRR1, RIP14, Nuclear Receptor Subfamily 1, Group H, Member 4, Bile acid receptor, Farnesol receptor HRR-1, Retinoid X receptor-interacting protein 14), Rabbit
FXR (Farnesoid X Receptor, NR1H4, BAR, FXR, HRR1, RIP14, Nuclear Receptor Subfamily 1, Group H, Member 4, Bile acid receptor, Farnesol receptor HRR-1, Retinoid X receptor-interacting protein 14), Rabbit
FXR (Farnesoid X Receptor, NR1H4, BAR, FXR, HRR1, RIP14, Nuclear Receptor Subfamily 1, Group H, Member 4, Bile acid receptor, Farnesol receptor HRR-1, Retinoid X receptor-interacting protein 14), Rabbit
Biozol Catalog Number:
USB-363179
Supplier Catalog Number:
363179
Alternative Catalog Number:
USB-363179-200
Manufacturer:
US Biological
Host:
Rabbit
Category:
Antikörper
Application:
ELISA, IHC, WB
Immunogen:
Recombinant protein corresponding to aa211-486 of human FXR, expressed in E. coli.
The farnesoid X receptor (FXR),is a nuclear hormone receptor with activity similar to that seen in other steroid receptors such as estrogen or progesterone but more similar in form to PPAR, LXR and RXR. FXR is encoded by the NR1H4 gene. FXR is expressed at high levels in the liver and intestine. Chenodeoxycholic acid and other bile acids are natural ligands for FXR. Like other steroid receptors, when activated, FXR translocates to the cell nucleus, forms a dimer (in this case a heterodimer with RXR) and binds to hormone response elements on DNA which elicits expression or transrepression of gene products. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 0.01-2ug/ml Immunohistochemistry: 5-20ug/ml Immunocytochemistry: 5-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap
