CH 223191 is a specific and potent antagonist to the aryl hydrocarbon receptor (AhR), a ligand-dependent transcription factor that is involved in drug and xenobiotic metabolism. Unlike other AhR antagonists, it does not react with the estrogen receptor and is observed to effect AhR-dependent reporter gene expression in human, mouse, rat, and guinea pig cell lines. CH223191 is reported to exhibit AHR-independent pro-proliferative properties. Synonyms: AhR Antagonist, CH223191, AGN-PC-0KP4EW, Aryl hydrocarbon receptor antagonist, 2-methyl-N-[2-methyl-4-[(2-methylphenyl)diazenyl]phenyl]pyrazole-3-carboxamide CAS No: 301326-22-7 Molecular Formula: C19H19N5 Molecular Weight: 333.4 Purity: 95% Appearance: Crystalline solid Solubility: Soluble in organic solvents such as ethanol and DMSO. Applications: FA Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. Stable for 6 months after receipt.
Molecular Weight:
333.4
CAS Number:
[301326-22-7]
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