EX 527 (Selisistat, EX527, SIRT1 Inhibitor III), CAS [[49843-98-3]]

Product Overview

• Article Name: EX 527 (Selisistat, EX527, SIRT1 Inhibitor III), CAS [[49843-98-3]]
• Biozol Catalog Number: USB-366881
• Supplier Catalog Number: 366881
• Alternative Catalog Number: USB-366881-10
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Synonyms: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide, Selisistat, EX527, SIRT1 Inhibitor III Chemical Name: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide Molecular Formula: C13 H13 ClN 2 Molecular Weight: 248.7 CAS Number: 49843-98-3 Purity: 98% Applications: FA Appearance: Crystalline solid Description: EX 527 is a selective inhibitor of NAD-dependent deacetylase sirtuin-1 (SIRT1) to the exclusion of histone deacetylases (HDACs) and other sirtuins. It is reported that inhibiting SIRT1 is associated with increasing insulin sensitivity and effecting other metabolic regulatory functions. EX 527 was used to determine that the inactivation of SirT1 stimulates tumor cell proliferation. Storage: Soluble in organic solvents such as ethanol and DMSO. DMSO up to 75mM

Product Properties

• Molecular Weight: 248.7
• Purity: Highly Purified (~98%)
• Form: Supplied as a crystalline solid.
• CAS Number: [49843-98-3]