SB 525334 (SB-525334, 6-(2-(tert-Butyl)-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)quinoxaline), CAS [[356559-20-1]]

Product Overview

• Article Name: SB 525334 (SB-525334, 6-(2-(tert-Butyl)-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)quinoxaline), CAS [[356559-20-1]]
• Biozol Catalog Number: USB-366912
• Supplier Catalog Number: 366912
• Alternative Catalog Number: USB-366912-10,USB-366912-50
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Synonyms: SB-525334, 6-(2-(tert-Butyl)-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)quinoxaline Chemical Name: 6-[2-tert-butyl-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl]quinoxaline Molecular Formula: C21H21N5 Molecular Weight: 343.4 CAS Number: 356559-20-1 Purity: 98% Applications: FA Appearance: Crystalline solid Description: SB 525334 is a selective and potent inhibitor of the TGF-Beta receptor 1 (ALK5). It exhibits no inhibition of ALK2, ALK3, and ALK6. It blocks the activation of Smad2/3 by TGF-beta1 in renal proximal tubule cells and attenuates bleomycin-induced pulmonary fibrosis. Solubility: Soluble in organic solvents such as DMSO. DMSO up to 100mM. Storage: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 343.4
• Purity: Highly Purified (~98%)
• Form: Supplied as a crystalline solid.
• CAS Number: [356559-20-1]