CECR1, also known as adenosine deaminase CECR1 isoform, is a member of a family of adenosine deaminase-related growth factors. Adenosine deaminase is one of the key enzymes of purine nucleotide metabolism. CECR1 is a secreted protein that is expressed in many tissues, with the highest expression in lymphoblasts, heart, lung, and placenta. Source: Recombinant protein corresponding to human CECR1, fused to His-tag at C-terminal, expressed in E. coli Molecular Weight: ~56.9kD (490aa) 50-70KD (SDS-PAGE under reducing conditions.) AA Sequence: IDETRAHLLL KEKMMRLGGR LVLNTKEELA NERLMTLKIA EMKEAMRTLI FPPSMHFFQA KHLIERSQVF NILRMMPKGA ALHLHDIGIV YRPHCHICFT PRGIMQFRFA HPTPRPSEKC SKWILLEDYR KRVQNVTEFD DSLLRNFTLV TQHPEVIYTN QNVVWSKFET IFFTISGLIH RSMQEFYEDN VLYMEIRARL LPVYELSGEH HDEEWSVKTY QEVAQKFVET HPEFIGIKII YSDHRSKDVA VIAESIRMAM GLRIKFPTVV TGHSLHDYKE ALMIPAKDGV KLPYFFHAGE TDWQGTSIDR NILDALMLNT TRIGHGFALS KHPAVRTYSW KKDIPIEVCP ISNQVLKLVS MATGHPMVIS SDDPAMFGAK GLSYDFYEVF MGIGGMKADL RTLKQLAMNS IKYSTLLESE KNTFMEIWKK RWDKFIADVA TKLEHHHHHH TMDWLVRNVT YAPVFRDYVF AGFDLVGHED DLRNHPVATL Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
