Prss28, also known as serine protease 28, belongs to the S1 serine proteinase family with a conserved Histidine-Aspartic Acid-Serine catalytic triad. It exhibits mixed substrate specificity that silences signaling via proteinase-activated receptors. It is involved with embryo hatching and its activity is important for successful implantation. Source: Recombinant protein corresponding to aa27-274 from mouse Prss28, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~28.7kD (256aa) 28-40kD (SDS-PAGE under reducing conditions) Amino Acid Sequence: KPVGIVGGQC TPPGKWPWQV SLRMYSYEVN SWVHICGGSI IHPQWILTAA HCIQSQDADP AVYRVQVGEV YLYKEQELLN ISRIIIHPDY NDVSKRFDLA LMQLTALLVT STNVSPVSLP KDSSTFDSTD QCWLVGWGNL LQRVPLQPPY QLHEVKIPIQ DNKSCKRAYR KKSSDEHKAV AIFDDMLCAG TSGRGPCFGD SGGPLVCWKS NKWIQVGVVS KGIDCSNNLP SIFSRVQSSL AWIHQHIQLE HHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
