S100A8, Recombinant, Human, aa1-93, His-Myc-Tag (S100 Calcium Binding Protein A8)
Biozol Catalog Number:
USB-369125
Supplier Catalog Number:
369125
Alternative Catalog Number:
USB-369125-100,USB-369125-500
Manufacturer:
US Biological
Category:
Molekularbiologie
S100A8, also known as S100A8 isoform d. S100A8 is a member of the S100 family, EF-hand superfamily of Calcium binding proteins. S100A8 protein is localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Altered expression of this protein is associated with the disease cystic fibrosis. Source: Recombinant protein corresponding to aa1-93 from human S100A8, fused to His-Tag at N-terminal, and fused to Myc-Tag at C-terminal, expressed in E. coli. Molecular Weight: ~14.5kD (127aa) confirmed by MALDI-TOF Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMLTELE KALNSIIDVY HKYSLIKGNF HAVYRDDLKK LLETECPQYI RKKGADVWFK ELDINTDGAV NFQEFLILVI KMGVAAHKKS HEESHKEEQK LISEEDL Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
