ST6GAL1, also known as beta-galactoside alpha-2,6-sialyltransferase 1, is a type II membrane protein localized in the trans-Golgi network and catalyzes 2,6-sialylation of Gal beta 1,4-GlcNAc structures on N-glycans. It is highly expressed in the liver and also expressed in most other tissues to some extent. Its deficiency causes abnormalities in B cell immunoreactivity. Source: Recombinant protein corresponding to aa27-406 from human ST6GAL1, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~44.6kD (389aa) 40-57kD (SDS-PAGE under reducing conditions) Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
