T-cell immunoreceptor with Ig and ITIM Domains, Recombinant, Human, aa22-141, His-SUMO-Tag (TIGIT)

Product Overview

• Article Name: T-cell immunoreceptor with Ig and ITIM Domains, Recombinant, Human, aa22-141, His-SUMO-Tag (TIGIT)
• Biozol Catalog Number: USB-370806
• Supplier Catalog Number: 370806
• Alternative Catalog Number: USB-370806-20,USB-370806-100
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. Source: Partial recombinant protein corresponding to aa22-141 from human TIGIT, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~29.1kD Amino Acid Sequence: MMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGTYTGRIFLEVLESSVAEHGARFQIP Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 29.1
• UniProt: Q495A1
• Purity: 90% (SDS-PAGE)
• Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.