Tetrahydrobiopterin (BH4, THB), also known as sapropterin, is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin (5-hydroxytryptamine, 5-HT), melatonin, dopamine, norepinephrine (noradrenaline), epinephrine (adrenaline), and is a cofactor for the production of nitric oxide (NO) by the nitric oxide synthases.[1] Chemically, its structure is that of a reduced pteridine derivative. Synonyms: (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride 6R-BH4 CAS Number: 69056-38-8, 17528-72-2 Chemical Formula: C9H15N5O3.2HCl Molecular Weight: 314.17 Appearance: White to light yellow powder Assay (Titration): 96 - 101% Purity (HPLC): 97% Loss on Drying: 2%
Molecular Weight:
314.17
Purity:
97% (HPLC)
Form:
White to light yellow powder
CAS Number:
[17528-72-2]
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