CSNK1A1, Recombinant. Human, aa2-337, His-Tag (Casein Kinase I Isoform alpha)

Product Overview

• Article Name: CSNK1A1, Recombinant. Human, aa2-337, His-Tag (Casein Kinase I Isoform alpha)
• Biozol Catalog Number: USB-372885
• Supplier Catalog Number: 372885
• Alternative Catalog Number: USB-372885-20,USB-372885-100,USB-372885-1
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at Ser-45. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. Source: Recombinant protein corresponding to aa2-337 from human Casein Kinase I Isoform alpha, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~42.8kD Amino Acid Sequence: ASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 42.8
• UniProt: P48729
• Purity: 90% (SDS-PAGE)
• Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.