DOK5, Recombinant, Human, aa1-198, His-SUMO-Tag (Docking Protein 5)

Product Overview

• Article Name: DOK5, Recombinant, Human, aa1-198, His-SUMO-Tag (Docking Protein 5)
• Biozol Catalog Number: USB-373092
• Supplier Catalog Number: 373092
• Alternative Catalog Number: USB-373092-20,USB-373092-100,USB-373092-1
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. Source: Recombinant protein corresponding to aa1-198 from human DOK5, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~38.8kD Amino Acid Sequence: MECVGTRINDISLGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQSVKNSMLQMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTETFPAYRSEH Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 38.8
• UniProt: Q9P104
• Purity: 90% (SDS-PAGE)
• Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.