DR1, Recombinant, Human, aa1-176, GST-Tag ( Protein Dr1)

Catalog Number: USB-373095
Article Name: DR1, Recombinant, Human, aa1-176, GST-Tag ( Protein Dr1)
Biozol Catalog Number: USB-373095
Supplier Catalog Number: 373095
Alternative Catalog Number: USB-373095-20,USB-373095-100,USB-373095-1
Manufacturer: US Biological
Category: Molekularbiologie
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Source: Recombinant protein corresponding to aa1-176 from human DR1, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~46.3kD Amino Acid Sequence: ASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 46.3
UniProt: Q01658
Purity: 90% (SDS-PAGE)
Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.