Kcne2, Recombinant, Rat, aa1-123, His-Tag (Potassium Voltage-gated Channel Subfamily E Member 2)

Product Overview

• Article Name: Kcne2, Recombinant, Rat, aa1-123, His-Tag (Potassium Voltage-gated Channel Subfamily E Member 2)
• Biozol Catalog Number: USB-373903
• Supplier Catalog Number: 373903
• Alternative Catalog Number: USB-373903-20,USB-373903-100
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-type current. May associate with KCNQ1/KCLQT1 and elicit a voltage-independent current. Source: Recombinant protein corresponding to aa1-123 from rat Kcne2, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~18.4kD Amino Acid Sequence: MTTLANLTQTLEDAFKKVFITYMDSWRRNTTAEQQALQARVDAENFYYVILYLMVMIGMFAFIVVAILVSTVKSKRREHSQDPYHQYIVEDWQQKYRSQILHLEDSKATIHENLGATGFTVSP Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 18.4
• UniProt: P63161
• Purity: 90% (SDS-PAGE)
• Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.