Nerve Growth Factor, Beta, Recombinant, Rat, aa122-241, His-Tag (Ngfbeta, Beta-NGF)

Product Overview

• Article Name: Nerve Growth Factor, Beta, Recombinant, Rat, aa122-241, His-Tag (Ngfbeta, Beta-NGF)
• Biozol Catalog Number: USB-374401
• Supplier Catalog Number: 374401
• Alternative Catalog Number: USB-374401-20,USB-374401-100
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI. Source: Recombinant protein corresponding to aa122-241 from rat Ngf, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~15.4kD Amino Acid Sequence: SSTHPVFHMGEFSVCDSVSVWVGDKTTATDIKGKEVTVLGEVNINNSVFKQYFFETKCRAPNPVESGCRGIDSKHWNSYCTTTHTFVKALTTDDKQAAWRFIRIDTACVCVLSRKAARRG Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 15.4
• UniProt: P25427
• Purity: 90% (SDS-PAGE)
• Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.