Protein Bottleneck, Recombinant, Drosophila melanogaster, aa1-303, His-Tag (Bnk)

Catalog Number: USB-374875
Article Name: Protein Bottleneck, Recombinant, Drosophila melanogaster, aa1-303, His-Tag (Bnk)
Biozol Catalog Number: USB-374875
Supplier Catalog Number: 374875
Alternative Catalog Number: USB-374875-20, USB-374875-100
Manufacturer: US Biological
Category: Molekularbiologie
Acts as a regulator of the microfilament network governing cellularization of the embryo. Determines the timing of a key conformational transition in the cortical microfilament network: the proper coordination of membrane invagination and basal closure of the cells. To do this, bnk possibly physically links neighboring contractile units of the early cycle 14 microfilament network in a manner that prevents basal constriction until the proper stage has been reached. Bnk together with nullo and Sry-alpha may provide auxiliary functions, by acting both to stabilize a large and dynamic microfilament structure and regulate its functions. Source: Recombinant protein corresponding to aa1-303 from drosophila melanogaster Protein Bottleneck, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~37.6kD Amino Acid Sequence: MSISTFNFQFYNYKLSPSSPGFGSTASRSSSSCISELEMDIDEDMSAQPTITSTPKPRFTSQLAVELAKTEPGNGISPLRPKLHTAQKRWSMELREKVLEMSKRNNGQEKPQTARQQEQRQPQEQPLQQEELQHQQQEPTVTDKINFFNKLTNTFESGFSKLMPQASSTNNRFIAMLRTARPQNVATTTANSSTANSFLGSDHSLSGSVTGQVPPPKPKRLSATTAQFATPHVPAMGVGKGGSQRKCSLRRKPSMDKSRATISRQSSSASVRTQNHAIMEDLSLVVPVRLRIAEYEQRISMSA Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 37.6
UniProt: P40794
Purity: 90% (SDS-PAGE)
Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.