Reg3g, Recombinant, Mouse, aa27-174, His-Tag (Regenerating Islet-derived Protein 3-gamma)

Product Overview

• Article Name: Reg3g, Recombinant, Mouse, aa27-174, His-Tag (Regenerating Islet-derived Protein 3-gamma)
• Biozol Catalog Number: USB-375027
• Supplier Catalog Number: 375027
• Alternative Catalog Number: USB-375027-20,USB-375027-100
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury. Source: Recombinant protein corresponding to aa27-174 from mouse Reg3g, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~20.3kD Amino Acid Sequence: EVAKKDAPSSRSSCPKGSRAYGSYCYALFSVSKNWYDADMACQKRPSGHLVSVLSGAEASFLSSMIKSSGNSGQYVWIGLHDPTLGYEPNRGGWEWSNADVMNYINWETNPSSSSGNHCGTLSRASGFLKWRENYCNLELPYVCKFKA Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 20.3
• UniProt: O09049
• Purity: 90% (SDS-PAGE)
• Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.