WDR5, Recombinant, Human, aa2-334, His-SUMO-Tag (WD Repeat-containing Protein 5)

Product Overview

• Article Name: WDR5, Recombinant, Human, aa2-334, His-SUMO-Tag (WD Repeat-containing Protein 5)
• Biozol Catalog Number: USB-375859
• Supplier Catalog Number: 375859
• Alternative Catalog Number: USB-375859-20,USB-375859-100,USB-375859-1
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Contributes to histone modification. May position the N-terminal of histone H3 for efficient trimethylation at Lys-4. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation. Source: Recombinant protein corresponding to aa2-334 from human WDR5, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~52.5kD Amino Acid Sequence: ATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 52.5
• UniProt: P61964
• Purity: 90% (SDS-PAGE)
• Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.