CD244, Recombinant, Human, aa19-224, hIgG-His-Tag (Natural Killer Cell Receptor 2B4 Isoform 1, 2B4, NAIL, NKR2B4, Nmrk, SLAMF4)

Product Overview

• Article Name: CD244, Recombinant, Human, aa19-224, hIgG-His-Tag (Natural Killer Cell Receptor 2B4 Isoform 1, 2B4, NAIL, NKR2B4, Nmrk, SLAMF4)
• Biozol Catalog Number: USB-377733
• Supplier Catalog Number: 377733
• Alternative Catalog Number: USB-377733-50
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

CD244, also known as natural killer cell receptor 2B4 isoform 1, is a natural killer and T cell immunoglobulin superfamily surface protein and ligand of CD48. It is a cell surface glycoprotein related to CD2 and implicated in the regulation of natural killer and T lymphocyte function. It is expressed on all human NK cells, a subpopulation of T cells, basophils and monocytes. It activates NK cell mediated cytotoxicity, induces secretion of IFN-gamma and matrix metalloproteinases, and NK cell invasiveness. Source: Recombinant protein corresponding to aa19-224 from human CD244, fused to hIgG-His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~50.2kD (448aa), 50-70kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: ADLGKGCQGS ADHVVSISGV PLQLQPNSIQ TKVDSIAWKK LLPSQNGFHH ILKWENGSLP SNTSNDRFSF IVKNLSLLIK AAQQQDSGLY CLEVTSISGK VQTATFQVFV FDKVEKPRLQ GQGKILDRGR CQVALSCLVS RDGNVSYAWY RGSKLIQTAG NLTYLDEEVD INGTHTYTCN VSNPVSWESH TLNLTQDCQN AHQEFRFWPL EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GKHHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Properties

• Molecular Weight: 50.2
• NCBI: 057466
• UniProt: Q9BZW8
• Purity: ~90% (SDS-PAGE)
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.