CGB3, Recombinant, Human, aa21-165, His-Tag (Choriogonadotropin Subunit beta 3, CGB, CGB5, CGB7, CGB8, hCGB)
Catalog Number:
USB-377761
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| Article Name: | CGB3, Recombinant, Human, aa21-165, His-Tag (Choriogonadotropin Subunit beta 3, CGB, CGB5, CGB7, CGB8, hCGB) |
| Biozol Catalog Number: | USB-377761 |
| Supplier Catalog Number: | 377761 |
| Alternative Catalog Number: | USB-377761-10 |
| Manufacturer: | US Biological |
| Category: | Molekularbiologie |
| CGB3, also known as choriogonadotropin subunit beta, is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). It stimulates the expression of GCM1 target genes, including the fusogenic protein syncytin-1, to promote placental cell fusion. It synthesized in large quantities by the developing placenta, reaching peak concentrations in maternal blood during the late first trimester and early midtrimester of pregnancy. It is expressed exclusively by trophoblasts. It is an important biomarker in pregnancy and oncology, where it is routinely detected and quantified by specific immunoassays. Source: Recombinant protein corresponding to aa21-165 from human CGB3, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~16.6kD (154aa), 18-28kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: ADPSKEPLRP RCRPINATLA VEKEGCPVCI TVNTTICAGY CPTMTRVLQG VLPALPQVVC NYRDVRFESI RLPGCPRGVN PVVSYAVALS CQCALCRRST TDCGGPKDHP LTCDDPRFQD SSSSKAPPPS LPSPSRLPGP SDTPILPQHH HHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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