Creg1, Recombinant, Mouse, aa32-220, His-Tag (Cellular Repressor of E1A-stimulated Genes 1, Creg)

Product Overview

• Article Name: Creg1, Recombinant, Mouse, aa32-220, His-Tag (Cellular Repressor of E1A-stimulated Genes 1, Creg)
• Biozol Catalog Number: USB-377771
• Supplier Catalog Number: 377771
• Alternative Catalog Number: USB-377771-100,USB-377771-500
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Creg1, also known as Cellular repressor of E1A-stimulated genes1, was antagonizes transcriptional activation and cellular transformation by E1A. This protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. Creg1 increases EC filopodia formation and vascular assembly via ILK-Cdc42 activation and promotes neovascularization, which might be a therapeutic target for ischemic injury. Source: Recombinant protein corresponding to aa32-220 from mouse Creg1 protein, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~24kD (213aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMRGGRDH GDWDVDRRLP PLPPREDGPR VARFVTHVSD WGSLATISTI KEVRGWPFAD IISISDGPPG EGTGEPYMYL SPLQQAVSDL QENPEATLTM SLAQTVYCRN HGFDPQSPLC VHIMMSGTVT KVNKTEEDYA RDSLFVRHPE MKHWPSSHNW FFAKLKISRI WVLDYFGGPK VVTPEEYFNV TLQ Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 24
• NCBI: 035934
• UniProt: O88668
• Purity: 95% (SDS-PAGE)
• Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.15M sodium chloride, 10% glycerol.