GZMK, Recombinant, Human, aa27-264, His-Tag (Granzyme K, TRYP2)

Product Overview

• Article Name: GZMK, Recombinant, Human, aa27-264, His-Tag (Granzyme K, TRYP2)
• Biozol Catalog Number: USB-377832
• Supplier Catalog Number: 377832
• Alternative Catalog Number: USB-377832-50
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

GZMK, as known as Granzyme K, is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface nonself antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. Source: Recombinant protein corresponding to aa27-264 from human GZMK, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~26.9kD (247aa), 28-40kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: ADPIIGGKEV SPHSRPFMAS IQYGGHHVCG GVLIDPQWVL TAAHCQYRFT KGQSPTVVLG AHSLSKNEAS KQTLEIKKFI PFSRVTSDPQ SNDIMLVKLQ TAAKLNKHVK MLHIRSKTSL RSGTKCKVTG WGATDPDSLR PSDTLREVTV TVLSRKLCNS QSYYNGDPFI TKDMVCAGDA KGQKDSCKGD SGGPLICKGV FHAIVSGGHE CGVATKPGIY TLLTKKYQTW IKSNLVPPHT NHHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Properties

• Molecular Weight: 26.9
• NCBI: 002095
• UniProt: P49863
• Purity: ~95% (SDS-PAGE)
• Form: Supplied as a liquid in PBS, pH 7.4, 1mM DTT, 20% glycerol.