Hpgd, Recombinant, Mouse, aa1-269, His-Tag (Hydroxyprostaglandin Dehydrogenase, 15-PGDH)

Product Overview

• Article Name: Hpgd, Recombinant, Mouse, aa1-269, His-Tag (Hydroxyprostaglandin Dehydrogenase, 15-PGDH)
• Biozol Catalog Number: USB-377836
• Supplier Catalog Number: 377836
• Alternative Catalog Number: USB-377836-100,USB-377836-500
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Hpgd, also known as Hydroxyprostaglandin dehydrogenase, is a member of the short-chain dehydrogenases/reductases family. It metabolizes prostaglandins (PGs) to render them. Prostaglandins (PGs) play a crucial role in mediating parturition events, and their synthesis and metabolism are regulated by PGH synthase and 15-hydroxy-PG dehydrogenase (PGDH), respectively. Hpgd, a COX-2 oncogene antagonist, is a TGF-beta- induced suppressor of human gastrointestinal cancers. Source: Recombinant protein corresponding to aa1-269 from mouse Hpgd, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~31.6kD (292aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMHVNGKV ALVTGAAQGI GKAFAEALLL HGAKVALVDW NLEAGVKCKA ALDEQFEPQK TLFVQCDVAD QKQLRDTFRK VVDHFGRLDI LVNNAGVNNE KNWEQTLQIN LVSVISGTYL GLDYMSKQNG GEGGIIINMS SLAGLMPVAQ QPVYCASKHG IIGFTRSAAM AANLMKSGVR LNVICPGFVD TPILESIEKE ENMGQYIEYK DQIKAMMKFY GVLHPSTIAN GLINLIEDDA LNGAIMKITA SKGIHFQDYD ISPLLVKAPL TS Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 31.6
• NCBI: 032304
• UniProt: Q8VCC1
• Purity: 95% (SDS-PAGE)
• Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 30% glycerol.