IL6, Recombinant, Canine, aa21-207, His-Tag (Interleukin-6, IL-6)

Catalog Number: USB-377864
Article Name: IL6, Recombinant, Canine, aa21-207, His-Tag (Interleukin-6, IL-6)
Biozol Catalog Number: USB-377864
Supplier Catalog Number: 377864
Alternative Catalog Number: USB-377864-50
Manufacturer: US Biological
Category: Molekularbiologie
IL6, as known as Interleukin-6, is a phosphorylated and variably glycosylated cytokine. It is secreted by T cells and macrophages to stimulate immune response during infection and after trauma, especially burns or other tissue damage leading to inflammation. Also, this protein can function as an anti-inflammatory molecule, as in skeletal muscle where it is secreted in response to exercise. Source: Recombinant protein corresponding to aa24-188 from canine IL6, fused to His-Tag at C terminal, expressed in insect cell. Molecular Weight: ~22kD (195aa), 18-28kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: FPTPGPLAGD SKDDATSNSL PLTSANKVEE LIKYILGKIS ALRKEMCDKF NKCEDSKEAL AENNLHLPKL EGKDGCFQSG FNQETCLTRI TTGLVEFQLH LNILQNNYEG DKENVKSVHM STKILVQMLK SKVKNQDEVT TPDPTTDASL QAILQSQDEC VKHTTIHLIL RSLEDFLQFS LRAVRIMLEH HHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight: 22
NCBI: 001003301
UniProt: P41323
Purity: ~95% (SDS-PAGE)
Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.