PPP1CC, Recombinant, Human, aa1-323, His-Tag (Serine/Threonine-Protein Phosphatase PP1-gamma Catalytic Subunit, PP1gamma, PPP1G)

Catalog Number: USB-377938
Article Name: PPP1CC, Recombinant, Human, aa1-323, His-Tag (Serine/Threonine-Protein Phosphatase PP1-gamma Catalytic Subunit, PP1gamma, PPP1G)
Biozol Catalog Number: USB-377938
Supplier Catalog Number: 377938
Alternative Catalog Number: USB-377938-10,USB-377938-20,USB-377938-50,USB-377938-100,USB-377938-250
Manufacturer: US Biological
Category: Molekularbiologie
PPP1CC, also known as serine/threonine-protein phosphatase PP1-gamma catalytic subunit, is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. This protein is involved in regulation of ionic conductances and long-term synaptic plasticity and may play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II. Recombinant protein corresponding to aa1-323 from human PPP1CC, fused to His-Tag, expressed in E. coli. Uniprot/Accession: NP_002701 Specific Activity: >700units/mg Unit Definition: Defined as the amount of enzyme that hydrolyze 1nmole of p-nitrophenyl phosphate (pNPP)/minute at pH 7.5 at 37C. Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MADLDKLNID SIIQRLLEVR GSKPGKNVQL QENEIRGLCL KSREIFLSQP ILLELEAPLK ICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS LETICLLLAY KIKYPENFFL LRGNHECASI NRIYGFYDEC KRRYNIKLWK TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL QSMEQIRRIM RPTDVPDQGL LCDLLWSDPD KDVLGWGEND RGVSFTFGAE VVAKFLHKHD LDLICRAHQV VEDGYEFFAK RQLVTLFSAP NYCGEFDNAG AMMSVDETLM CSFQILKPAE KKKPNATRPV TPPRGMITKQ AKK Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight: 39.1
NCBI: 002701
UniProt: P36873
Purity: 85% (SDS-PAGE under reducing conditons and visualized by coomassie blue stain)
Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 2mM DTT, 0.2M sodium chloride, 50% glycerol