PROCR, Recombinant, Human, aa18-210, hIgG-His-Tag (Endothelial Protein C Receptor, CCCA, CCD41, EPCR)
Biozol Catalog Number:
USB-377941
Supplier Catalog Number:
377941
Alternative Catalog Number:
USB-377941-50
Manufacturer:
US Biological
Category:
Molekularbiologie
PROCR, also known as endothelial protein C receptor, is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. It is a transmembrane glycoprotein expressed on vascular endothelial cells and functions as a negative regulator of thrombosis. Source: Recombinant protein corresponding to aa24-188 from human PROCR, fused to hIgG-His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~49.3kD (435aa), 40-57kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: ADPSQDASDG LQRLHMLQIS YFRDPYHVWY QGNASLGGHL THVLEGPDTN TTIIQLQPLQ EPESWARTQS GLQSYLLQFH GLVRLVHQER TLAFPLTIRC FLGCELPPEG SRAHVFFEVA VNGSSFVSFR PERALWQADT QVTSGVVTFT LQQLNAYNRT RYELREFLED TCVQYVQKHI SAENTKGSQT SRSYTSLEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
