SCN3B, Recombinant, Human, aa23-159, His-Tag (Sodium Channel Subunit beta-3, ATFB16, BRGDA7, HSA243396, SCNB3)

Product Overview

• Article Name: SCN3B, Recombinant, Human, aa23-159, His-Tag (Sodium Channel Subunit beta-3, ATFB16, BRGDA7, HSA243396, SCNB3)
• Biozol Catalog Number: USB-377961
• Supplier Catalog Number: 377961
• Alternative Catalog Number: USB-377961-50
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

SCN3B, also known as sodium channel subunit beta-3, is an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics. It was detected in brain, heart, kidney, lung, pancreas and skeletal muscle. It is expressed in adult mammalian skeletal muscle and can functionally couple to the skeletal muscle alpha subunit, SkM1. It associates with neurofascin through their extracellular immunoglobulin-like domain. Source: Recombinant protein corresponding to aa23-159 from human SCN3B, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~16.8kD (146aa), 18-28kD (SDS-PAGE under reducing conditions) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: ADPFPVCVEV PSETEAVQGN PMKLRCISCM KREEVEATTV VEWFYRPEGG KDFLIYEYRN GHQEVESPFQ GRLQWNGSKD LQDVSITVLN VTLNDSGLYT CNVSREFEFE AHRPFVKTTR LIPLRVTEEA GEDFTSVVSE HHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Properties

• Molecular Weight: 16.8
• NCBI: 060870
• UniProt: Q9NY72
• Purity: ~90% (SDS-PAGE)
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.