SH2D1B, Recombinant, Human, aa1-132, His-Tag (SH2 Domain-containing Protein 1B, EAT2)
Biozol Catalog Number:
USB-377966
Supplier Catalog Number:
377966
Alternative Catalog Number:
USB-377966-50
Manufacturer:
US Biological
Category:
Molekularbiologie
SH2D1B, also known as SH2 domain-containing protein 1B, is one of the proteins which activate NK cells. It plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells. Two isoforms of the human protein are produced by alternative splicing. Source: Recombinant protein corresponding to aa1-132 from human SH2D1B, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~16.4kD (141aa), 18-28kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: ADPMDLPYYH GRLTKQDCET LLLKEGVDGN FLLRDSESIP GVLCLCVSFK NIVYTYRIFR EKHGYYRIQT AEGSPKQVFP SLKELISKFE KPNQGMVVHL LKPIKRTSPS LRWRGLKLEL ETFVNSNSDY VDVLPHHHHH H Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
