SLAMF6, Recombinant, Human, aa22-226, His-Tag (SLAMF Family Member 6 Isoform 1, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000)
Catalog Number:
USB-377974
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| Article Name: | SLAMF6, Recombinant, Human, aa22-226, His-Tag (SLAMF Family Member 6 Isoform 1, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000) |
| Biozol Catalog Number: | USB-377974 |
| Supplier Catalog Number: | 377974 |
| Alternative Catalog Number: | USB-377974-50 |
| Manufacturer: | US Biological |
| Category: | Molekularbiologie |
| SLAMF6, also known as SLAM family member 6 isoform 1, belongs to the SLAM family of immune cell receptors. It is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28- independent manner. This protein is expressed on NK-, T-, and B cells. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. Source: Recombinant protein corresponding to aa22-226 from human SLAMF6 protein, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~24.1kD (214aa), 28-40kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: ADPQSSLTPL MVNGILGESV TLPLEFPAGE KVNFITWLFN ETSLAFIVPH ETKSPEIHVT NPKQGKRLNF TQSYSLQLSN LKMEDTGSYR AQISTKTSAK LSSYTLRILR QLRNIQVTNH SQLFQNMTCE LHLTCSVEDA DDNVSFRWEA LGNTLSSQPN LTVSWDPRIS SEQDYTCIAE NAVSNLSFSV SAQKLCEDVK IQYTDTKMHH HHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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