Bourjotinolone A is a prenylated flavonoid that inhibits the production of inflammatory cytokines in human cells. Bourjotinolone A has been shown to inhibit the nuclear factor kappa-light-chain-enhancer and factor kappa-light-chain-enhancer, which are transcription factors that regulate proinflammatory cytokine production. This compound also inhibits the activation of lipopolysaccharide (LPS)-stimulated RAW264.7 cells by blocking the binding of LPS to toll-like receptor 4, preventing the release of proinflammatory cytokines. Bourjotinolone A has been isolated from plants belonging to the Meliaceae family and is used as a natural product for research purposes. Synonyms: Bourjotinolone A, (13alpha,14beta,17alpha,20S,23R,24S)-21,24-Epoxy-23,25-dihydroxylanost-7-en-3-one CAS No: 6985-35-9 Molecular Formula: C30H48O4 Molecular Weight: 472.71 Purity: 97% Appearance: White powder Melting Point: 176C (lit) Boling Point: 583.150.0C (lit) pKa: 14.390.60 (lit) Solubility: Chloroform, Acetone Storage and Stability: Store at -20C. Stable for 6 months after receipt.
Molecular Weight:
472.71
CAS Number:
[6985-35-9]
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