| Azithromycin B (Azithromycin EP Impurity B), is an impurity of Azithromycin, a semi-synthetic macrolide antibiotic, and related to Erythromycin A. Synonyms: (2R,3R,4S,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy]-2-ethyl-4,10-dihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy]-1-Oxa-6-azacyclopentadecan-15-one, Azithromycin EP Impurity B CAS No: 307974-61-4 Molecular Formula: C38H72N2O11 Molecular Weight: 732.99 Appearance: White to yellow solid Purity: 95% Solubility: Chloroform (Slightly), Methanol (Slightly) Method for Determining Identity: Proton NMR Spectroscopic and Mass Spectrometric analysis TLC Conditions: SiO2, Dichloromethane: Methanol: Ammounium Hydroxide = 9:1:0.2, Visualized with AMCS and KMnO4, SIngle spot, Rf=0.50 Elemental Analysis: Calculated: %C: 62.27, %H: 9.90, %N: 3.82 Diethyl Ether: As Reported Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C for 6 months after receipt. |
