3-Methoxy-4,5,7-trihydroxyisoflavone, CAS [[36190-95-1]]

Product Overview

• Article Name: 3-Methoxy-4,5,7-trihydroxyisoflavone, CAS [[36190-95-1]]
• Biozol Catalog Number: USB-427727
• Supplier Catalog Number: 427727
• Alternative Catalog Number: USB-427727-10,USB-427727-100
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

3-Methoxy-4,5,7-trihydroxyisoflavone is a derivative of Genistein (G350000), a compound that exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. Molecular Formula: C16H12O6 Molecular Weight: 300.26 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 300.26
• CAS Number: [36190-95-1]