4-Chloro-3-fluoroaniline is used in the synthesis of Methyl 5-Chloro-4-fluoro-1H-indole-2-carboxylate, a key intermediate towards phosphoindole inhibitors of HIV non-nucleoside reverse transcriptase. 4-Chloro-3-fluoroaniline is also used in the synthesis of 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib (D289540) which is an impurity of the tyrosine kinase inhibitor Gefitinib (G304000). Molecular Formula: C6H5ClFN Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) Molecular Weight: 145.56 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
145.56
Form:
Supplied as a Off-White to Pale Yellow Solid
CAS Number:
[367-22-6]
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