5-Methoxyindole-3-acetonitrile-d2 is a labelled analogue of 5-Methoxyindole-3-acetonitrile (M262818), which is a versatile reactant used in the preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment. It is also used in the synthesis of carboline analogs as potent MAPKAP-K2 inhibitors. 5-Methoxyindole-3-acetonitrile-d2 is also an intermediate in synthesizing Melatonin-d4 (M215002), a hormone, mediates photoperiodicity in mammals, inhibits cerebellar nitric oxide synthetase, peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action. Molecular Formula: C11H8D2N2O Solubility: Dichloromethane, Ethyl Acetate, Methanol Molecular Weight: 188.22 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
188.22
Form:
Supplied as a Light Brown Solid
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