| Caffeine-13C3 is a labelled analogue of Caffeine, a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. In humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. Caffeine is a cardiac and respiratory stimulant, diuretic. Caffeine is toxic at sufficiently high doses. A study at Johns Hopkins University indicates that caffeine can improve pattern separation memory. Synonyms: 3,7-Dihydro-1,3,7-tri(methyl-13C)-1H-purine-2,6-dione, 1,4,6-Trimethyl-1H-imidazo[4,5-b]pyridine-5,7(4H,6H)-dione-13C3, 1,3,7-Trimethylxanthine-13C3, 7-Methyltheophylline-13C3, Alert-Pep-13C3, Cafalgine-13C3, Cafeina-13C3, Caffedrine-13C3, Caffein-13C3, Cafipel-13C3, DHCplus-13C3, Dasin-13C3, Diurex-13C3, Durvitan-13C3, Guaranine-13C3, Hycomine-13C3, Koffein-13C3, Mateina-13C3, Methyltheobromine-13C3, Miudol-13C3, NSC 5036-13C3, New Cetamol-13C3, No-Doz-13C3, Palergot-C-13C3, Phensal-13C3, Refreshn-13C3, SK 65 Compound-13C3, Shape Plus-13C3, Stay Alert-13C3, Stim-13C3, Synalgos-13C3, Thein-13C3, Theine-13C3, Tri-Aqua-13C3, Wigraine-13C3 CAS No: 78072-66-9 unlabelled: 58-08-2 Molecular Formula: C5C3H10N4O2 Molecular Weight: 197.15 Purity: 98% Appearance: White solid Melting Point: 234-237C Solubility: DMSO (Slightly), Methanol (Slightly) Method for Determining Identity: 1H NMR (DMSO-d6), 13C NMR (DMSO-d6) and Mass Spectrometric Analysis TLC Conditions: SiO2, Dichloromethane: Methanol= 9:1, Visualized with UV and AMCS, Single spot, Rf=0.60 Elemental Analysis: Calculated: %C: 48.71, %H: 5.11, %N: 28.4 Normalized Intensity: 13C0= 0.00%, 13C1=0.00%, 13C2=3.90%, 13C3=96.10% Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures. |
